From Chapter 1:
"'It requires no effort of the fancy to picture these three men [Shakespeare, Bacon and Raleigh] as lounging in a window of Durham House, puffing the new Indian weed from silver bowls, discussing the highest themes in poetry and science, while gazing on the flower-beds and the river, the darting barges of dame and cavalier, and the distant pavilions of Paris garden and the Globe.'" This is a pure "effort of the fancy" so far as Bacon and Shakespeare are concerned. Shakespeare's absolute silence about tobacco forbids us to assume that he smoked; but of Raleigh the picture may be true enough. The house had, as Aubrey tells us, "a little turret that looked into and over the Thames, and had the prospect which is as pleasant perhaps as any in the world"; and it would be strange indeed if the owner of the noble house did not often smoke a contemplative pipe in the window of that pleasant turret.

From Chapter 7:
With the reign of Queen Anne tobacco had entered on a period, destined to be of long duration, when smoking was to a very large extent under a social ban. Pipe-smoking was unfashionable—that is to say, was not practised by men of fashion, and was for the most part regarded as "low" or provincial—from the time named until well into the reign of Queen Victoria. The social taboo was by no means universal—some of the exceptions will be noted in these pages—but speaking broadly, the general, almost universal smoking of tobacco which had been characteristic of the earlier decades of the seventeenth century did not again prevail until within living memory.