From Chapter 1:
"Tarlton, as other gentlemen used, at the first comming up of tobacco, did take it more for fashion's sake than otherwise, and being in a roome, set between two men overcome with wine, and they never seeing the like, wondered at it, and seeing the vapour come out of Tarlton's nose, cryed out, fire, fire, and threw a cup of wine in Tarlton's face. Make no more stirre, quoth Tarlton, the fire is quenched: if the sheriffes come, it will turne to a fine, as the custome is. And drinking that againe, fie, sayes the other, what a stinke it makes; I am almost poysoned. If it offend, saies Tarlton, let every one take a little of the smell, and so the savour will quickly goe: but tobacco whiffes made them leave him to pay all."

From Chapter 8:
More than one writer of recent days has absurdly misrepresented Johnson as a smoker. The author of a book on tobacco published a few years ago wrote—"Dr. Johnson smoked like a furnace"—a grotesquely untrue statement—and "all his friends, Goldsmith, Reynolds, Garrick, were his companions in tobacco-worship." Reynolds, we know—

When they talk'd of their Raphaels, Corregios, and stuff,
He shifted his trumpet, and only took snuff.

Johnson and all his company took snuff, as every one in the fashionable world, and a great many others outside that charmed circle, did; but Johnson did not smoke, and I doubt whether any of the others did.