From Chapter 1:
So far Hariot's "Report" regarded tobacco from the medicinal point of view only; but it is important to note that he goes on to describe his personal experience of the practice of smoking in words that suggest the pleasurable nature of the experience. He says: "We ourselves during the time we were there used to suck it after their maner, as also since our returne, and have found maine [? manie] rare and wonderful experiments of the vertues thereof: of which the relation woulde require a volume by itselfe: the use of it by so manie of late, men and women of great calling as else, and some learned Physitians also, is sufficient witness."

From Chapter 5:
The belief in the prophylactic power of tobacco was, however, very generally held. When Mr. Samuel Pepys on June 7, 1665, for the first time saw several houses marked with the ominous red cross, and the words "Lord, have mercy upon us" chalked upon the doors, he felt so ill at ease that he was obliged to buy some roll tobacco to smell and chew. There is nothing to show that Pepys even smoked, which considering his proficiency in the arts of good-fellowship, is perhaps a little surprising. Defoe, in his fictitious but graphic "Journal of the Plague Year in London," says that the sexton of one of the London parishes, who personally handled a large number of the victims, never had the distemper at all, but lived about twenty years after it, and was sexton of the parish to the time of his death. This man, according to Defoe, "never used any preservative against the infection other than holding garlic and rue in his mouth, and smoking tobacco."